Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.47 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.47 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140044 | 0.84 | MTOR (0.54) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20140600 | 0.83 | KDM4E (0.54) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20156930 | 0.82 | MTOR (0.46) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20157005 | 0.81 | CHRM4 (0.47) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20157004 | 0.81 | CHRM4 (0.47) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20140664 | 0.81 | MTOR (0.57) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20156887 | 0.80 | PPARG (0.46) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20156931 | 0.80 | MTOR (0.51) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20157021 | 0.80 | SLC6A7 (0.46) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20156927 | 0.80 | MTOR (0.47) | MTORRPTORMLST8ALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |