SCHEMBL20158288

SCHEMBL20158288

COC(=O)COCCOCCOCCOCCONC(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 6/20 0.40
▸ CA12 O43570 6/20 0.40
▸ CA14 Q9ULX7 2/20 0.40
▸ APLNR P35414 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.33
▸ MAOA P21397 1/20 0.32
▸ MAOB P27338 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ CA1 P00915 6/20 0.32
▸ CA7 P43166 2/20 0.32
▸ DGAT1 O75907 1/20 0.32
▸ MEN1 O00255 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ CA9 Q16790 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20158449 0.95 CA12 (0.37) CA2CA12CA14APLNRTDP1
SCHEMBL5494091 0.88 APLNR (0.40) CA2CA12CA14APLNRTDP1
SCHEMBL20158289 0.85 APLNR (0.37) CA2CA12CA14APLNRTDP1
SCHEMBL18906911 0.85 APLNR (0.37) CA2CA12CA14APLNRTDP1
SCHEMBL18906915 0.85 APLNR (0.37) CA2CA12CA14APLNRTDP1
SCHEMBL22515382 0.85 CA2 (0.36) CA2CA12CA14APLNRTDP1
SCHEMBL21694996 0.84 APLNR (0.40) CA2CA12CA14APLNRTDP1
SCHEMBL22339730 0.83 ADORA1 (0.37) CA2CA12CA14APLNRTDP1
SCHEMBL22030517 0.83 CA12 (0.46) CA2CA12CA14APLNRTDP1
SCHEMBL25143061 0.81 APLNR (0.36) CA2CA12CA14APLNRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11135306-B2 Antibody-drug conjugates CHO Pharma Inc. (TW) 2021-10-05 — — US disclosed
US-20190328895-A1 ANTIBODY-DRUG CONJUGATES CHO Pharma Inc. (TW) 2019-10-31 — — US disclosed
US-20180133340-A1 ANTIBODY-DRUG CONJUGATES CHO Pharma Inc. (TW) 2018-05-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190328895-A1 ANTIBODY-DRUG CONJUGATES CSGALNACT1, ADCY1, NEU1 CA2 510/4885CA12 59/4885CA14 147/4885
US-20180133340-A1 ANTIBODY-DRUG CONJUGATES CSGALNACT1, ST6GAL1, PA2G4 CA2 552/4885CA12 97/4885CA14 216/4885
US-11135306-B2 Antibody-drug conjugates CSGALNACT1, ST6GAL1, PA2G4 CA2 552/4885CA12 97/4885CA14 216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback