Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20158288 | 0.95 | CA2 (0.40) | CA12CA2CA14APLNRTDP1 | |
| SCHEMBL5494091 | 0.84 | APLNR (0.40) | CA12CA2CA14APLNRTDP1 | |
| SCHEMBL20158289 | 0.81 | APLNR (0.37) | CA12CA2CA14APLNRTDP1 | |
| SCHEMBL18906915 | 0.81 | APLNR (0.37) | CA12CA2CA14APLNRTDP1 | |
| SCHEMBL18906911 | 0.81 | APLNR (0.37) | CA12CA2CA14APLNRTDP1 | |
| SCHEMBL22515382 | 0.81 | CA2 (0.36) | CA12CA2CA14APLNRTDP1 | |
| SCHEMBL21694996 | 0.80 | APLNR (0.40) | CA12CA2CA14APLNRTDP1 | |
| SCHEMBL22339730 | 0.80 | ADORA1 (0.37) | CA12CA2CA14APLNRTDP1 | |
| SCHEMBL22030517 | 0.79 | CA12 (0.46) | CA12CA2CA14APLNRTDP1 | |
| SCHEMBL30737403 | 0.78 | TDP1 (0.56) | CA12CA2TDP1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018090045-A1 | ANTIBODY-DRUG CONJUGATES | CHO PHARMA INC (TW) | 2018-05-17 | — | — | WO | disclosed |