Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249539 | 0.89 | HSD17B10 (0.46) | PREPHSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL26077743 | 0.85 | ATM (0.45) | PREPHSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL14209868 | 0.82 | PREP (0.43) | PREPHSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL7328713 | 0.80 | HSD17B10 (0.49) | HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL202301 | 0.79 | ACE (0.48) | PREPHSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL202300 | 0.79 | ACE (0.48) | PREPHSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL1022969 | 0.79 | ACE (0.48) | PREPHSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL19414808 | 0.77 | HSD17B10 (0.61) | HSD17B10SMN1; SMN2EPHX2KLK7HPGD | |
| SCHEMBL895773 | 0.77 | HSD17B10 (0.61) | HSD17B10SMN1; SMN2EPHX2KLK7HPGD | |
| SCHEMBL7286305 | 0.77 | HSD17B10 (0.61) | HSD17B10SMN1; SMN2EPHX2KLK7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067266-A1 | CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |