Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | DRD3 | P35462 | 3/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | KHK | P50053 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | C1S | P09871 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.40 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20141027 | 0.99 | DRD2 (0.61) | DRD2DRD3NOTUMKHKALOX5 | |
| SCHEMBL6811968 | 0.82 | MAPT (0.44) | DRD2DRD3NOTUMKHKMAPT | |
| SCHEMBL2594613 | 0.81 | KDM4E (0.49) | KHKMAPTMLNR | |
| SCHEMBL2594614 | 0.81 | KDM4E (0.49) | KHKMAPTMLNR | |
| SCHEMBL6125344 | 0.81 | KDM4E (0.49) | KHKMAPTMLNR | |
| Hydrochloric Acid SCHEMBL709249 | 0.80 | KDM4E (0.47) | KHKMAPTMLNR | |
| Hydrochloric Acid SCHEMBL709248 | 0.80 | KDM4E (0.47) | KHKMAPTMLNR | |
| SCHEMBL315161 | 0.80 | ADRB1 (0.63) | NOTUMKHKALOX5MAPT | |
| SCHEMBL8109027 | 0.79 | KHK (0.50) | DRD2DRD3KHKMAPT | |
| SCHEMBL4240000 | 0.79 | HTR3E (0.61) | NOTUMKHKALOX5MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |