Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.45 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159115 | 0.91 | MTOR (0.55) | HRH3MAPTPTGS1PTGS2POLB | |
| SCHEMBL20159024 | 0.83 | MTOR (0.64) | HRH3POLBMTORRPTORMLST8 | |
| SCHEMBL20159286 | 0.82 | MTOR (0.51) | HRH3POLBMTORRPTORMLST8 | |
| SCHEMBL20159079 | 0.81 | MTOR (0.52) | HRH3POLBMTORRPTORMLST8 | |
| SCHEMBL20159066 | 0.81 | MTOR (0.45) | HRH3PTGS1PTGS2POLBMTOR | |
| SCHEMBL20159006 | 0.81 | CHRM4 (0.47) | HRH3PTGS1PTGS2 | |
| SCHEMBL20159166 | 0.80 | POLB (0.55) | HRH3POLBMTORRPTORMLST8 | |
| SCHEMBL20159007 | 0.80 | POLB (0.55) | HRH3POLBMTORRPTORMLST8 | |
| SCHEMBL20159009 | 0.79 | PTGS1 (0.46) | HRH3PTGS1PTGS2POLBMTOR | |
| SCHEMBL20159109 | 0.79 | MTOR (0.50) | PTGS1PTGS2MTORRPTORMLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |