Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.48 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RBP4 | P02753 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159024 | 0.85 | MTOR (0.64) | HTR7DRD2HTR2AMTORRPTOR | |
| SCHEMBL20159036 | 0.83 | MTOR (0.58) | HTR7KDM4EDRD2HTR2AMTOR | |
| SCHEMBL20159115 | 0.82 | MTOR (0.55) | HTR7SMN1; SMN2MTORRPTORMLST8 | |
| SCHEMBL20159079 | 0.81 | MTOR (0.52) | HTR7DRD2HTR2AMTORRPTOR | |
| SCHEMBL20159286 | 0.81 | MTOR (0.51) | HTR7MTORRPTORMLST8HRH3 | |
| SCHEMBL20139225 | 0.81 | MTOR (0.50) | HTR7DRD2HTR2AMTORRPTOR | |
| SCHEMBL20140477 | 0.80 | HTR7 (0.58) | HTR7KDM4EALDH1A1DRD2MTOR | |
| SCHEMBL20158999 | 0.79 | HTR7 (0.47) | HTR7ALDH1A1DRD2HTR2AGAA | |
| SCHEMBL20139747 | 0.79 | MTOR (0.60) | HTR7ALDH1A1DRD2MTORRPTOR | |
| Trifluoroacetic Acid SCHEMBL20139757 | 0.77 | MTOR (0.50) | HTR7DRD2HTR2AMTORRPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |