Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.34 |
| ▸ | DUT | P33316 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4503124 | 0.81 | ADRA2A (0.43) | DGAT1PDE10ADUTKLKB1 | |
| SCHEMBL26913294 | 0.75 | DGAT1 (0.39) | DGAT1PDE10A | |
| SCHEMBL30684286 | 0.75 | DGAT1 (0.39) | DGAT1PDE10A | |
| SCHEMBL27657190 | 0.75 | DGAT1 (0.37) | DGAT1PDE10A | |
| SCHEMBL31358007 | 0.75 | DGAT1 (0.41) | DGAT1PDE10A | |
| SCHEMBL6030125 | 0.74 | DGAT1 (0.40) | DGAT1PDE10ADUT | |
| SCHEMBL30018075 | 0.74 | DGAT1 (0.38) | DGAT1PDE10ADUT | |
| SCHEMBL31357962 | 0.74 | DGAT1 (0.36) | DGAT1PDE10A | |
| SCHEMBL29079932 | 0.74 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL30799248 | 0.73 | DGAT1 (0.37) | DGAT1PDE10ADUTKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |