Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 11/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159143 | 0.88 | MIF (0.42) | MIFDRD2BRD4CA12CA1 | |
| SCHEMBL22923512 | 0.85 | MIF (0.44) | MIFDRD2BRD4MAPTRECQL | |
| SCHEMBL22923793 | 0.82 | MIF (0.34) | MIFDRD2MAPTPDE4B | |
| SCHEMBL20159475 | 0.81 | NAMPT (0.48) | — | |
| SCHEMBL20142970 | 0.74 | TP53 (0.36) | MAPTPDE4B | |
| SCHEMBL22923673 | 0.69 | MEN1 (0.35) | MIFDRD2BRD4MAPTPDE4B | |
| SCHEMBL22923561 | 0.69 | CD274 (0.37) | MIFDRD2MAPT | |
| SCHEMBL20159528 | 0.65 | PDE4B (0.40) | PDE4B | |
| SCHEMBL24257354 | 0.65 | DRD2 (0.66) | DRD2 | |
| SCHEMBL19977078 | 0.64 | DYRK1A (0.45) | DRD2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086703-A1 | DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-17 | — | — | WO | disclosed |