Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 9/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.38 |
| ▸ | PDE4A | P27815 | 8/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159214 | 0.94 | HRH3 (0.41) | PDE4DPDE4BPDE4APDE4CCES2 | |
| SCHEMBL20159105 | 0.94 | CES2 (0.43) | PDE4DPDE4BPDE4APDE4CCES2 | |
| SCHEMBL20142915 | 0.91 | PDE3B (0.39) | PDE4DPDE4BPDE4APDE4CCES2 | |
| SCHEMBL20142922 | 0.91 | PDE4A (0.40) | PDE4DPDE4BPDE4APDE4CCES2 | |
| SCHEMBL20138907 | 0.91 | PDE4A (0.40) | PDE4DPDE4BPDE4APDE4CCES2 | |
| SCHEMBL20159213 | 0.91 | PDE4A (0.40) | PDE4DPDE4BPDE4APDE4CCES2 | |
| SCHEMBL20142927 | 0.81 | PDE4A (0.40) | PDE4DPDE4BPDE4APDE4CCYP19A1 | |
| SCHEMBL20138813 | 0.81 | PDE4A (0.40) | PDE4DPDE4BPDE4APDE4CCYP19A1 | |
| SCHEMBL20159190 | 0.81 | PDE4A (0.40) | PDE4DPDE4BPDE4APDE4CCYP19A1 | |
| SCHEMBL20159391 | 0.78 | PDE4A (0.38) | PDE4DPDE4BPDE4APDE4CHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867279-A | Novel oxopyridazinyl-phenyl-carbohydrazone acyldinitrile compounds and use thereof | 韩国科学技术研究院 | 2023-03-28 | — | — | CN | disclosed |
| WO-2018086703-A1 | DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-17 | — | — | WO | disclosed |