Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 3/20 | 0.44 |
| ▸ | LDHB | P07195 | 3/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748855 | 0.84 | BCL2 (0.50) | ALDH1A1ALOX15HIF1AHSD17B10LDHA | |
| SCHEMBL8092285 | 0.83 | BCL2 (0.54) | ALDH1A1ALOX15HIF1AHSD17B10LDHA | |
| 2,5-Xylidine SCHEMBL8130848 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL13815123 | 0.80 | ALDH1A1 (0.42) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL7904072 | 0.78 | BCL2 (0.45) | ALDH1A1ALOX15HSD17B10LDHALDHB | |
| SCHEMBL14294088 | 0.77 | HTR2A (0.46) | ALDH1A1LDHALDHBBCL2BCL2L1 | |
| SCHEMBL30290875 | 0.77 | ALDH1A1 (0.73) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL4649847 | 0.77 | BCL2 (0.40) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL22188467 | 0.76 | BCL2 (0.42) | ALDH1A1ALOX15HSD17B10LDHALDHB | |
| SCHEMBL31402366 | 0.76 | BCL2 (0.42) | ALDH1A1ALOX15HIF1AHSD17B10LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888691-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| WO-2018086139-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2018-05-17 | — | — | WO | disclosed |