SCHEMBL2015995

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2018437	0.90	HTR2C (0.41)	BRD4HTR2CHTR6KMT2APKM
	SCHEMBL2014853	0.89	BRD4 (0.49)	BRD4HTR2CHTR6
	SCHEMBL691881	0.89	BRD4 (0.47)	BRD4HTR2CHTR6MAPTKMT2A
	SCHEMBL2014809	0.87	HTR6 (0.47)	BRD4HTR6ALDH1A1
	SCHEMBL2021459	0.87	HTR2C (0.40)	BRD4HTR2CHTR6PKM
	SCHEMBL2015259	0.87	HTR6 (0.45)	BRD4HTR2CHTR6CASP3GAA
	SCHEMBL2016951	0.86	BRD4 (0.49)	BRD4HTR2CHTR6PKM
	SCHEMBL2014952	0.86	DDB1 (0.49)	BRD4HTR2CHTR6
	SCHEMBL2015014	0.85	SMN1; SMN2 (0.52)	BRD4HTR2CHTR6CASP3ALDH1A1
	SCHEMBL2014308	0.84	HTR6 (0.49)	HTR2CHTR6KMT2ATDP1AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.