Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14246825 | 0.86 | L3MBTL1 (0.41) | L3MBTL1RXFP1BRD9BRD4TSHR | |
| SCHEMBL20160352 | 0.84 | CYP1A2 (0.36) | L3MBTL1RXFP1NNMTBRD9BRD4 | |
| SCHEMBL20160235 | 0.83 | NNMT (0.34) | L3MBTL1RXFP1NNMTBRD9PDE4B | |
| SCHEMBL16140295 | 0.82 | RXFP1 (0.38) | L3MBTL1RXFP1BRD9BRD4CREBBP | |
| SCHEMBL16244413 | 0.75 | RXFP1 (0.45) | L3MBTL1RXFP1BRD9BRD4CREBBP | |
| SCHEMBL15711661 | 0.74 | RXFP1 (0.47) | L3MBTL1RXFP1BRD9BRD4CREBBP | |
| SCHEMBL16244643 | 0.74 | BRD9 (0.50) | L3MBTL1RXFP1BRD9BRD4CREBBP | |
| SCHEMBL6620694 | 0.72 | RXFP1 (0.42) | L3MBTL1RXFP1BRD9BRD4CREBBP | |
| SCHEMBL16244397 | 0.72 | RXFP1 (0.37) | L3MBTL1RXFP1BRD9BRD4CREBBP | |
| SCHEMBL11283623 | 0.70 | CASP1 (0.33) | NNMTSYKCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086585-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |