Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16268761 | 0.82 | MEN1 (0.36) | L3MBTL1BRD4 | |
| SCHEMBL16244286 | 0.81 | L3MBTL1 (0.46) | L3MBTL1BRD4BRD2BRD3 | |
| SCHEMBL14784056 | 0.78 | — | — | |
| SCHEMBL25260596 | 0.78 | PIM1 (0.31) | BRD4BRD2BRD3 | |
| SCHEMBL20160086 | 0.78 | ATAD2 (0.36) | L3MBTL1HTTBRD4BRD2BRD3 | |
| SCHEMBL20160353 | 0.78 | BRD4 (0.30) | BRD4BRD2BRD3 | |
| SCHEMBL16268588 | 0.75 | LMNA (0.39) | L3MBTL1BRD4BRD2BRD3 | |
| SCHEMBL25105540 | 0.74 | HTT (0.33) | L3MBTL1HTT | |
| SCHEMBL25103350 | 0.73 | NMT1 (0.33) | L3MBTL1HTT | |
| SCHEMBL20600772 | 0.73 | L3MBTL1 (0.35) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086585-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |