SCHEMBL20160263

SCHEMBL20160263

CNC(=O)C(Cc1ccccc1)NC(=O)C(C)NC

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 13/20 0.61
FCER2 P06734 2/20 0.61
MMP2 P08253 14/20 0.61
MMP3 P08254 8/20 0.61
MMP9 P14780 3/20 0.60
MMP8 P22894 3/20 0.60
MMP7 P09237 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21788079 0.90 MMP9 (0.51) MMP1FCER2MMP2MMP3MMP9
SCHEMBL22457529 0.89 MME (0.63) MMP2MMP9MMP7
SCHEMBL30576703 0.88 LTA4H (0.58)
SCHEMBL30576710 0.88 LTA4H (0.58)
SCHEMBL13744303 0.88 ALDH1A1 (0.53) MMP1FCER2MMP2MMP3MMP7
SCHEMBL25139614 0.88 MMP1 (0.64) MMP1FCER2MMP2MMP3MMP9
SCHEMBL22962378 0.88 MMP1 (0.64) MMP1FCER2MMP2MMP3MMP9
SCHEMBL19361059 0.88 MMP1 (0.64) MMP1FCER2MMP2MMP3MMP9
SCHEMBL13884333 0.88 MMP1 (0.64) MMP1FCER2MMP2MMP3MMP9
SCHEMBL21988101 0.84 MMP1 (0.63) MMP1FCER2MMP2MMP3MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023078021-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 WO disclosed
WO-2022078524-A2 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-04-21 WO disclosed
WO-2021212638-A1 CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2021-10-28 WO disclosed
EP-3888691-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS Hangzhou Dac Biotech Co., Ltd. (CN) 2021-10-06 EP disclosed
EP-3862023-A1 CONJUGATES OF CELL-BINDING MOLECULES WITH CYTOTOXIC AGENTS Hangzhou DAC Biotech Co, Ltd (CN) 2021-08-11 EP disclosed
WO-2020257998-A1 A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS HANGZHOU DAC BIOTECH CO., LTD (CN) 2020-12-30 WO disclosed
WO-2020155017-A1 A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS HANGZHOU DAC BIOTECH CO., LTD (CN) 2020-08-06 WO disclosed
WO-2018086139-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD (CN) 2018-05-17 WO disclosed