Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 7/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25316059 | 0.76 | PDIA6 (0.42) | GPR119 | |
| SCHEMBL26544849 | 0.75 | CYP19A1 (0.46) | PARP15PARP10SCN9APARP2BRD4 | |
| SCHEMBL13589518 | 0.74 | PTGS2 (0.53) | PARP15PARP10PARP2BRD4GPR119 | |
| SCHEMBL28012174 | 0.74 | PARP15 (0.43) | PARP15PARP10SCN9APARP2BRD4 | |
| SCHEMBL25316752 | 0.74 | L3MBTL1 (0.42) | CNR2 | |
| SCHEMBL1850715 | 0.73 | PARP10 (0.46) | PARP15PARP10PARP2SLC6A2SLC6A4 | |
| SCHEMBL13589519 | 0.73 | DDB1 (0.48) | BRD4 | |
| SCHEMBL20160101 | 0.71 | BRD4 (0.55) | BRD4 | |
| SCHEMBL2548494 | 0.70 | PARP10 (0.46) | PARP15PARP10PARP2SLC6A2SLC6A4 | |
| SCHEMBL1853454 | 0.70 | PARP10 (0.41) | PARP15PARP10SCN9APARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086585-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |