Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20160339 | 0.77 | BRD4 (0.52) | TRPA1BRD4 | |
| SCHEMBL30498824 | 0.70 | PTGS2 (0.56) | BRD4 | |
| SCHEMBL15067969 | 0.70 | PTGS2 (0.56) | BRD4 | |
| SCHEMBL28641777 | 0.70 | GAA (0.53) | NR1I2PPARGAGTR2MEN1BLM | |
| SCHEMBL20159992 | 0.68 | BRD4 (0.57) | BRD4 | |
| SCHEMBL30159449 | 0.68 | TRPA1 (0.53) | TRPA1HSPB1 | |
| SCHEMBL15068172 | 0.68 | EPAS1 (0.52) | HSPB1BRD4 | |
| SCHEMBL21904840 | 0.68 | HSPB1 (0.72) | HSPB1MEN1KMT2A | |
| SCHEMBL25191080 | 0.68 | TRPA1 (0.45) | TRPA1HSPB1BRD4 | |
| SCHEMBL10456772 | 0.67 | TRPA1 (0.56) | TRPA1HSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086585-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |