SCHEMBL20160441

SCHEMBL20160441

c1ccc(-n2cnc3cc(-c4ccc5c6ccccc6c6ccccc6c5c4)ccc32)cc1

nearest known ligand 0.64

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDR P35968 3/20 0.64
FGFR1 P11362 12/20 0.59
HTT P42858 1/20 0.56
SRC P12931 1/20 0.53
ALDH1A1 P00352 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19228785 0.88 HTT (0.56) KDRFGFR1HTTSRCALDH1A1
SCHEMBL12135624 0.87 KDR (0.76) KDRFGFR1HTTSRCALDH1A1
SCHEMBL7677283 0.82 KDR (0.68) KDRFGFR1HTTSRCALDH1A1
SCHEMBL23099348 0.79 KDR (0.57) KDRFGFR1HTTSRCALDH1A1
SCHEMBL16656278 0.78 KDR (0.67) KDRFGFR1HTTSRC
SCHEMBL7679742 0.78 KDR (0.64) KDRFGFR1HTTSRCALDH1A1
SCHEMBL5942362 0.78 FGFR1 (0.79) KDRFGFR1SRCALDH1A1
SCHEMBL7683792 0.78 KDR (1.00) KDRFGFR1HTTSRCALDH1A1
SCHEMBL27285256 0.78 KDR (0.63) KDRFGFR1HTTSRCALDH1A1
SCHEMBL23189498 0.77 KDR (0.44) KDRFGFR1HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11545637-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-01-03 US disclosed
US-20220302396-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION (US) 2022-09-22 US disclosed
US-20220127291-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-04-28 US disclosed
US-10957866-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-03-23 US disclosed
US-10897016-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-01-19 US disclosed
US-20180212163-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-26 US disclosed
US-20180138425-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180212163-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG KDR 925/4885FGFR1 2905/4885HTT 2520/4885
US-20180138425-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES DDT, OCIAD1, OCIAD2 KDR 2567/4885FGFR1 2938/4885HTT 1372/4885
US-11545637-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG KDR 925/4885FGFR1 2905/4885HTT 2520/4885
US-10897016-B2 Organic electroluminescent materials and devices DDT, OCIAD1, OCIAD2 KDR 2567/4885FGFR1 2938/4885HTT 1372/4885
US-10957866-B2 Organic electroluminescent materials and devices TYR, YAP1, PAXBP1 KDR 907/4885FGFR1 1295/4885HTT 2837/4885
US-20220127291-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RER1, OCIAD2, OXSR1 KDR 672/4885FGFR1 1800/4885HTT 3434/4885
US-20220302396-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS JUND, DRD2, DRD1 KDR 488/4885FGFR1 963/4885HTT 670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.