SCHEMBL20160627

SCHEMBL20160627

CCC(C)c1cccc2c1sc1ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
GPR3 P46089 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.40
RAB9A P51151 2/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
ATM Q13315 1/20 0.40
PARP14 Q460N5 1/20 0.38
ALOX5 P09917 1/20 0.38
MAPT P10636 3/20 0.37
TLR8 Q9NR97 1/20 0.37
TLR7 Q9NYK1 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
EGFR P00533 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9963712 1.00 TSHR (0.46) TSHRGPR3L3MBTL1RAB9AKDM4E
SCHEMBL1102404 0.82 GPR3 (0.48) TSHRGPR3L3MBTL1RAB9AKDM4E
SCHEMBL23775993 0.80 TSHR (0.46) TSHRGPR3RAB9AKDM4EALDH1A1
SCHEMBL2384224 0.80 TSHR (0.46) TSHRGPR3RAB9AKDM4EALDH1A1
SCHEMBL23056977 0.79 GPR3 (0.45) GPR3L3MBTL1RAB9AKDM4EALDH1A1
SCHEMBL22161912 0.79 GPR3 (0.45) GPR3L3MBTL1RAB9AKDM4EALDH1A1
SCHEMBL24555871 0.76 GPR3 (0.38) GPR3L3MBTL1RAB9AKDM4EALDH1A1
SCHEMBL22924517 0.75 GPR3 (0.48) GPR3L3MBTL1RAB9AKDM4EALDH1A1
SCHEMBL10015065 0.75 GPR3 (0.48) GPR3L3MBTL1RAB9AKDM4EALDH1A1
SCHEMBL11072799 0.75 MAPT (0.47) TSHRL3MBTL1RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212135-A1 LIGHT EMITTING ELEMENT, AMINE COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-06 US disclosed
US-10580996-B2 Polycyclic compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2020-03-03 US disclosed
US-20180138421-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212135-A1 LIGHT EMITTING ELEMENT, AMINE COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME SLC1A2, SLC18A2, SLC18A1 TSHR 2165/4885GPR3 2555/4885L3MBTL1 1920/4885
US-20180138421-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CRY2, NR2E3, CRY1 TSHR 4377/4885GPR3 2950/4885L3MBTL1 644/4885
US-10580996-B2 Polycyclic compound and organic light-emitting element comprising same CRY2, NR2E3, CRY1 TSHR 4377/4885GPR3 2950/4885L3MBTL1 644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.