Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | WNT1 | P04628 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20160685 | 0.84 | KDM1A (0.39) | KDM1A | |
| SCHEMBL17113908 | 0.80 | ACHE (0.42) | CYP3A4 | |
| SCHEMBL17096046 | 0.78 | GNAI3 (0.41) | CYP3A4HTR4WNT1GSK3BDYRK1A | |
| SCHEMBL18199696 | 0.78 | CYP3A4 (0.40) | CYP3A4HTR4WNT1GSK3BDYRK1A | |
| SCHEMBL20356359 | 0.78 | CYP3A4 (0.35) | CYP3A4HTR4WNT1GSK3BDYRK1A | |
| SCHEMBL27976164 | 0.78 | CYP3A4 (0.37) | CYP3A4HTR4WNT1GSK3BDYRK1A | |
| SCHEMBL16095117 | 0.77 | CYP3A4 (0.36) | CYP3A4HTR4 | |
| SCHEMBL22310778 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL14684548 | 0.75 | HTR4 (0.37) | CYP3A4HTR4KDM1AWNT1GSK3B | |
| SCHEMBL16096218 | 0.75 | CYP3A4 (0.35) | CYP3A4HTR4GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976337-B1 | 5-AMINO-QUINOLINE-8-CARBOXAMIDE DERIVATIVES AS 5-HT4 RECEPTOR AGONISTS | SUVEN LIFE SCIENCES LTD (IN) | 2018-05-02 | — | — | EP | disclosed |