Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.41 |
| ▸ | ATP4B | P51164 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30535930 | 0.85 | L3MBTL1 (0.48) | L3MBTL1TSHRMEN1KMT2AHTT | |
| SCHEMBL15814340 | 0.85 | L3MBTL1 (0.48) | L3MBTL1TSHRMEN1KMT2AHTT | |
| SCHEMBL29779070 | 0.85 | L3MBTL1 (0.48) | L3MBTL1TSHRMEN1KMT2AHTT | |
| SCHEMBL15814471 | 0.85 | L3MBTL1 (0.48) | L3MBTL1TSHRMEN1KMT2AHTT | |
| SCHEMBL20160832 | 0.85 | TSHR (0.48) | L3MBTL1TSHRAOC3MEN1KMT2A | |
| SCHEMBL18526223 | 0.81 | MEN1 (0.46) | L3MBTL1TSHRAOC3MEN1KMT2A | |
| SCHEMBL21419430 | 0.80 | AOC3 (0.41) | L3MBTL1TSHRAOC3MEN1KMT2A | |
| SCHEMBL17874237 | 0.79 | AOC3 (0.41) | L3MBTL1TSHRAOC3HTTSTAT3 | |
| SCHEMBL18526460 | 0.79 | L3MBTL1 (0.42) | L3MBTL1TSHRMEN1KMT2AHTT | |
| SCHEMBL15813749 | 0.79 | USP28 (0.47) | L3MBTL1MEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086589-A1 | 1,5,7-TRI-SUBSTITUTED ISOQUINOLINE DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN MEDICINES | 上海海雁医药科技有限公司 | 2018-05-17 | — | — | WO | disclosed |