Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17874273 | 0.88 | L3MBTL1 (0.40) | L3MBTL1TSHRSTAT3HTTSMN1; SMN2 | |
| SCHEMBL17874288 | 0.83 | L3MBTL1 (0.36) | L3MBTL1TSHRSTAT3HTTSMN1; SMN2 | |
| SCHEMBL21419430 | 0.82 | AOC3 (0.41) | AOC3L3MBTL1TSHRSTAT3HTT | |
| SCHEMBL18526223 | 0.81 | MEN1 (0.46) | AOC3L3MBTL1TSHRSTAT3HTT | |
| SCHEMBL24644870 | 0.80 | L3MBTL1 (0.46) | L3MBTL1TSHRSTAT3HTTSMN1; SMN2 | |
| SCHEMBL20160880 | 0.79 | L3MBTL1 (0.48) | AOC3L3MBTL1TSHRSTAT3HTT | |
| SCHEMBL18526569 | 0.78 | AOC3 (0.43) | AOC3L3MBTL1TSHRSTAT3HTT | |
| SCHEMBL17874239 | 0.77 | KMT2A (0.43) | L3MBTL1TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20160832 | 0.76 | TSHR (0.48) | AOC3L3MBTL1TSHRSTAT3HTT | |
| Hydrochloric Acid SCHEMBL17874265 | 0.73 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1MAPTHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016102493-A1 | IMIDAZOPYRIDINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |
| WO-2016102493-A1 | IMIDAZOPYRIDINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |