SCHEMBL20161315

SCHEMBL20161315

CCCCCCOC(=O)C(C)C1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.39
GBA1 P04062 1/20 0.38
EPHX1 P07099 1/20 0.37
LMNA P02545 1/20 0.37
TSHR P16473 2/20 0.36
GBA2 Q9HCG7 1/20 0.36
SELL P14151 1/20 0.36
SELP P16109 1/20 0.36
TLR4 O00206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20158784 0.86 NAAA (0.39) NAAAGBA1EPHX1LMNATSHR
SCHEMBL20161571 0.84 MAPK1 (0.47) GBA2TLR4
SCHEMBL20161310 0.84 MAPK1 (0.47) GBA2TLR4
SCHEMBL20161305 0.84 MAPK1 (0.47) GBA2TLR4
SCHEMBL20161670 0.82 SELE (0.34)
SCHEMBL20161433 0.78 GBA2 (0.44) NAAAGBA1EPHX1TSHRGBA2
SCHEMBL20161420 0.77 MMP8 (0.42) NAAAGBA1EPHX1
SCHEMBL20161683 0.77 MMP8 (0.42) NAAAGBA1EPHX1
SCHEMBL20161569 0.74 FUCA1 (0.33)
SCHEMBL20161308 0.74 FUCA1 (0.31) TSHRSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11045411-B2 Process for treating keratin materials using amide, acid or ester c-glycoside derivatives, and cosmetic composition containing same L'OREAL (FR) 2021-06-29 US disclosed
US-20180133137-A1 PROCESS FOR TREATING KERATIN MATERIALS USING AMIDE, ACID OR ESTER C-GLYCOSIDE DERIVATIVES, AND COSMETIC COMPOSITION CONTAINING SAME L'OREAL (FR) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180133137-A1 PROCESS FOR TREATING KERATIN MATERIALS USING AMIDE, ACID OR ESTER C-GLYCOSIDE DERIVATIVES, AND COSMETIC COMPOSITION CONTAINING SAME KRT18, CUTA, GLA NAAA 232/4885GBA1 920/4885EPHX1 2974/4885
US-11045411-B2 Process for treating keratin materials using amide, acid or ester c-glycoside derivatives, and cosmetic composition containing same KRT18, CUTA, GLA NAAA 232/4885GBA1 920/4885EPHX1 2974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.