Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723136 | 0.94 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL7153351 | 0.89 | EGFR (0.50) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL11803623 | 0.87 | NR1H2 (0.44) | ALDH1A1NR1H2NR1H3EGFRERBB2 | |
| SCHEMBL2492761 | 0.86 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL7932826 | 0.85 | CA2 (0.47) | ALDH1A1CYP3A4TSHREGFRERBB2 | |
| SCHEMBL17663681 | 0.84 | EGFR (0.47) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL768272 | 0.84 | EGFR (0.47) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL2014159 | 0.84 | EGFR (0.47) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL20226249 | 0.83 | NR1H2 (0.36) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL20161341 | 0.83 | MAPT (0.43) | ALDH1A1CYP3A4TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164469-A | Preparation method of milone derivative | 杭华油墨股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| EP-2380567-B1 | MELANIN PRODUCTION INHIBITOR | POLA CHEM IND INC (JP) | 2019-01-16 | — | — | EP | disclosed |
| US-20160356723-A1 | Light-Up Probes Based On Fluorogens With Aggregation Induced Emission Characteristics For Cellular Imaging And Drug Screening | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-12-08 | — | — | US | disclosed |
| US-20160356723-A1 | Light-Up Probes Based On Fluorogens With Aggregation Induced Emission Characteristics For Cellular Imaging And Drug Screening | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-12-08 | — | — | US | disclosed |
| EP-3009123-A1 | MELANIN PRODUCTION INHIBITOR | Pola Chemical Industries Inc. (JP) | 2016-04-20 | — | — | EP | disclosed |
| US-20150328107-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2015-11-19 | — | — | US | disclosed |
| WO-2015112092-A2 | LIGHT-UP PROBES BASED ON FLUOROGENS WITH AGGREGATION INDUCED EMISSION CHARACTERISTICS FOR CELLULAR IMAGING AND DRUG SCREENING | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2015-07-30 | — | — | WO | disclosed |
| EP-2845587-A2 | Melanin production inhibitor | Pola Chemical Industries Inc. (JP) | 2015-03-11 | — | — | EP | disclosed |
| US-20140363389-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-12-11 | — | — | US | disclosed |
| US-8846012-B2 | Melanin production inhibitor | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-09-30 | — | — | US | disclosed |
| EP-2380567-A1 | MELANIN PRODUCTION INHIBITOR | Pola Chemical Industries Inc. (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-20110243865-A1 | MELANIN PRODUCTION INHIBITOR | POLA CHEMICAL INDUSTRIES INC. (JP) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160356723-A1 | Light-Up Probes Based On Fluorogens With Aggregation Induced Emission Characteristics For Cellular Imaging And Drug Screening | FOLH1, GGT1, GSTP1 | ALDH1A1 117/4885CYP3A4 194/4885TSHR 3518/4885 |
| US-20110243865-A1 | MELANIN PRODUCTION INHIBITOR | TYR, F12, TH | ALDH1A1 1292/4885CYP3A4 115/4885TSHR 100/4885 |
| US-20150328107-A1 | MELANIN PRODUCTION INHIBITOR | TYR, MC1R, F12 | ALDH1A1 1031/4885CYP3A4 106/4885TSHR 75/4885 |
| US-20140363389-A1 | MELANIN PRODUCTION INHIBITOR | TYR, F12, MC1R | ALDH1A1 1187/4885CYP3A4 104/4885TSHR 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.