Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10114131 | 0.91 | RXFP1 (0.75) | RXFP1TP53ALOX15CYP1A2CYP3A4 | |
| SCHEMBL3795179 | 0.89 | RXFP1 (0.68) | RXFP1TP53ALOX15CYP1A2CYP3A4 | |
| SCHEMBL17628697 | 0.88 | ALOX15 (0.69) | RXFP1TP53ALOX15CYP1A2TRPA1 | |
| SCHEMBL30128448 | 0.88 | ALOX15 (0.69) | RXFP1TP53ALOX15CYP1A2TRPA1 | |
| SCHEMBL10113849 | 0.86 | RXFP1 (0.79) | RXFP1TP53ALOX15CYP1A2TRPA1 | |
| SCHEMBL18166574 | 0.85 | RXFP1 (0.76) | RXFP1TP53ALOX15CYP1A2TRPA1 | |
| SCHEMBL10114522 | 0.84 | ALOX15 (0.78) | RXFP1TP53ALOX15CYP1A2CYP3A4 | |
| SCHEMBL10114298 | 0.84 | CYP1A2 (0.82) | RXFP1TP53ALOX15CYP1A2CYP3A4 | |
| SCHEMBL10114015 | 0.84 | RXFP1 (0.74) | RXFP1TP53ALOX15CYP1A2TRPA1 | |
| SCHEMBL17626253 | 0.84 | ALOX15 (0.74) | RXFP1TP53ALOX15CYP1A2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180133170-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | ELI LILLY AND COMPANY | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133170-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | TRPA1, TRPV1, TRPV3 | RXFP1 1374/4885TP53 4574/4885ALOX15 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.