Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2015311 | 0.87 | EGLN1 (0.46) | EGLN1FTOBBOX1PADI4ERN1 | |
| SCHEMBL20777914 | 0.68 | EGLN1 (0.46) | EGLN1FTOBBOX1KDM4EALDH1A1 | |
| SCHEMBL14842361 | 0.68 | TDP1 (0.52) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL2014951 | 0.68 | MEN1 (0.49) | PADI4KMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL29008365 | 0.66 | PADI4 (0.44) | PADI4ERN1KMT2AKDM4EMEN1 | |
| SCHEMBL23886136 | 0.65 | PLAU (0.47) | KMT2AKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL13728550 | 0.63 | EGLN1 (0.42) | EGLN1FTOBBOX1KMT2AKDM4E | |
| SCHEMBL2012510 | 0.63 | PTPN22 (0.48) | — | |
| SCHEMBL15563355 | 0.61 | ERN1 (0.60) | ERN1KMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL30917992 | 0.61 | ALDH1A1 (0.49) | KMT2AKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |