Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092162 | 0.72 | APOBEC3A (0.36) | HDAC1HDAC8 | |
| SCHEMBL19036600 | 0.71 | YTHDC1 (0.37) | — | |
| SCHEMBL9010481 | 0.68 | CYP2C19 (0.34) | PDE10AHDAC1 | |
| SCHEMBL30800978 | 0.63 | POLB (0.38) | — | |
| SCHEMBL22902731 | 0.61 | APOBEC3A (0.37) | — | |
| SCHEMBL9067856 | 0.60 | APOBEC3A (0.46) | HDAC1HDAC8 | |
| SCHEMBL12724350 | 0.60 | ALDH1A1 (0.44) | — | |
| SCHEMBL31332867 | 0.60 | ALDH1A1 (0.38) | HDAC1HDAC8 | |
| SCHEMBL9010469 | 0.60 | IKBKB (0.36) | HDAC1 | |
| SCHEMBL28861349 | 0.59 | ADORA2A (0.33) | HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180133170-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | ELI LILLY AND COMPANY | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133170-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | TRPA1, TRPV1, TRPV3 | PDE10A 945/4885HDAC1 1782/4885HDAC8 1676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.