Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | BCR | P11274 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.53 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20395687 | 0.89 | MAPT (0.52) | TOP2AALDH1A1MEN1KMT2AALPI | |
| SCHEMBL4919468 | 0.85 | MAPT (0.70) | TOP2AALDH1A1MEN1KMT2AALPI | |
| SCHEMBL935705 | 0.85 | MAPT (0.74) | TOP2AALDH1A1MEN1KMT2AALPI | |
| SCHEMBL20162268 | 0.85 | ALDH1A1 (0.57) | TOP2AALDH1A1MEN1KMT2AALPI | |
| SCHEMBL20162234 | 0.84 | MAPT (0.51) | TOP2AALDH1A1MEN1KMT2AALPG | |
| SCHEMBL7872344 | 0.83 | MEN1 (0.70) | TOP2AALDH1A1MEN1KMT2AALPI | |
| SCHEMBL30883297 | 0.82 | MAPT (0.58) | TOP2AALDH1A1MEN1KMT2AALPI | |
| SCHEMBL12693583 | 0.82 | MAPT (0.58) | TOP2AALDH1A1MEN1KMT2AALPI | |
| SCHEMBL16307895 | 0.82 | MAPT (0.74) | TOP2AALDH1A1MEN1KMT2AALPI | |
| SCHEMBL27216311 | 0.82 | MAPT (0.61) | TOP2AALDH1A1MEN1KMT2AALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | TOP2A 838/4885ALDH1A1 1313/4885MEN1 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.