Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALPG | P10696 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162234 | 0.84 | MAPT (0.51) | KDM4EALDH1A1TOP2AKMT2AMEN1 | |
| SCHEMBL23407471 | 0.84 | MEN1 (0.57) | KDM4EALDH1A1TOP2AKMT2AMEN1 | |
| SCHEMBL718131 | 0.81 | PKM (0.59) | KDM4EALDH1A1KMT2AMEN1EGFR | |
| SCHEMBL20162247 | 0.80 | PTP4A3 (0.43) | KDM4EALDH1A1TOP2AKMT2AMEN1 | |
| SCHEMBL23407459 | 0.80 | ALOX5 (0.47) | KDM4EALDH1A1TOP2AKMT2AMEN1 | |
| SCHEMBL23407473 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1TOP2AKMT2AMEN1 | |
| SCHEMBL14173718 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1TOP2AKMT2AMEN1 | |
| SCHEMBL23407462 | 0.78 | ESR1 (0.43) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9125329 | 0.77 | MEN1 (0.53) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9125332 | 0.77 | MEN1 (0.53) | KDM4EALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |