Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 1/20 | 0.43 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.43 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162246 | 0.89 | PTP4A3 (0.41) | PTP4A3PTP4A2PTP4A1KDM4EMEN1 | |
| SCHEMBL20162268 | 0.85 | ALDH1A1 (0.57) | KDM4EALDH1A1TOP2AMEN1KMT2A | |
| SCHEMBL2903666 | 0.84 | PTP4A3 (0.57) | PTP4A3PTP4A2PTP4A1KDM4EALDH1A1 | |
| SCHEMBL20162234 | 0.84 | MAPT (0.51) | KDM4EALDH1A1TOP2AMEN1KMT2A | |
| SCHEMBL23407471 | 0.84 | MEN1 (0.57) | PTP4A1KDM4EALDH1A1TOP2AMEN1 | |
| SCHEMBL20162278 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1TOP2AMEN1KMT2A | |
| SCHEMBL23407473 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1TOP2AMEN1KMT2A | |
| SCHEMBL23407459 | 0.80 | ALOX5 (0.47) | KDM4EALDH1A1TOP2AMEN1KMT2A | |
| SCHEMBL23407462 | 0.78 | ESR1 (0.43) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8734502 | 0.78 | NR1H4 (0.53) | KDM4EALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210161783-A1 | USE OF SPECIFIC BENZYLIDENE MALONATES FOR PROTECTING THE SKIN FROM CHEMICALLY INDUCED STRESS | MERCK PATENT GMBH (DE) | 2021-06-03 | — | — | US | disclosed |
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | PTP4A3 3582/4885PTP4A2 4139/4885PTP4A1 3983/4885 |
| US-20210161783-A1 | USE OF SPECIFIC BENZYLIDENE MALONATES FOR PROTECTING THE SKIN FROM CHEMICALLY INDUCED STRESS | MAL2, GAA, ME2 | PTP4A3 1356/4885PTP4A2 1439/4885PTP4A1 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.