Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.61 |
| ▸ | PTPRB | P23467 | 1/20 | 0.57 |
| ▸ | CDC25A | P30304 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 1/20 | 0.57 |
| ▸ | PTEN | P60484 | 1/20 | 0.57 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273986 | 1.00 | KEAP1 (0.61) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| Phenyl Propionic Acid SCHEMBL6660445 | 0.96 | KEAP1 (0.68) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL70271 | 0.90 | KEAP1 (0.74) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL1666941 | 0.89 | SMN1; SMN2 (0.63) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL5264276 | 0.89 | KEAP1 (0.61) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| Hydrochloric Acid SCHEMBL10982620 | 0.88 | KEAP1 (0.71) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL19313223 | 0.87 | MAPT (0.62) | KEAP1HDAC3MAPK1ADRA1AHDAC4 | |
| Hydrochloric Acid SCHEMBL27491907 | 0.87 | SMN1; SMN2 (0.61) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| Adipic Acid SCHEMBL272108 | 0.86 | MAPT (0.55) | KEAP1ENPP2LOXL2HDAC3MAPK1 | |
| Adipic Acid SCHEMBL5694409 | 0.85 | MAPT (0.53) | KEAP1FFAR1ENPP2LOXL2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101371199-B | Photoresist stripper composition for semiconductor manufacturing | TECHNO SEMICHEM CO LTD | 2012-05-30 | — | — | CN | claimed |
| CN-101371199-A | Photoresist stripper composition for semiconductor manufacturing | TECHNO SEMICHEM CO LTD (KR) | 2009-02-18 | — | — | CN | claimed |
| US-11945806-B2 | Stabilization of amyloidogenic immunoglobulin light chains | THE SCRIPPS RESEARCH INSTITUTE | 2024-04-02 | — | — | US | disclosed |
| US-20220204485-A1 | STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | THE SCRIPPS RESEARCH INSTITUTE | 2022-06-30 | — | — | US | disclosed |
| CN-114127050-A | Benzopyran and imidazole derivatives useful for stabilizing amyloidogenic immunoglobulin light chains | 斯克利普斯研究所 | 2022-03-01 | — | — | CN | disclosed |
| EP-3946604-A1 | BENZOPYRANE AND IMIDAZOLE DERIVATIVES USEFUL FOR THE STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | The Scripps Research Institute (US) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020205683-A1 | BENZOPYRANE AND IMIDAZOLE DERIVATIVES USEFUL FOR THE STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-10-08 | — | — | WO | disclosed |
| CN-109843866-A | YAP1 inhibitors targeting YAP1 interaction with OCT4 | H·李·莫菲特癌症中心研究有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-105481806-B | The synthetic method of the 5-membered ring compounds containing sulfuryl and application | 华南理工大学 | 2018-09-14 | — | — | CN | disclosed |
| CN-105777688-B | A kind of synthetic method of γ pyranone compounds | 中国药科大学 | 2017-12-15 | — | — | CN | disclosed |
| EP-2630196-B1 | CYANINE DYES AND THEIR CONJUGATES | LI COR INC (US) | 2017-09-06 | — | — | EP | disclosed |
| CN-1870999-A | Alkynes I | ASTRAZENECA AB (SE) | 2006-11-29 | — | — | CN | disclosed |
| CN-1826325-A | 4,5-dihydro-imidazole as P2X7 ion channel blockers | AVENTIS PHARMA INC (US) | 2006-08-30 | — | — | CN | disclosed |
| EP-1401434-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | ELI LILLY AND COMPANY (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100403-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |
| EP-0716661-B1 | PSEUDO- AND NON-PEPTIDE BRADYKININ RECEPTOR ANTAGONISTS | SCIOS INC (US) | 2000-04-05 | — | — | EP | disclosed |
| US-5541286-A | Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids | SCIOS NOVA INC. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0716661-A1 | PSEUDO- AND NON-PEPTIDE BRADYKININ RECEPTOR ANTAGONISTS | SCIOS NOVA INC. (US) | 1996-06-19 | — | — | EP | disclosed |
| US-5444048-A | Antiinflammatory agents, analgesics | SCIOS NOVA, INC. (US) | 1995-08-22 | — | — | US | disclosed |
| WO-1995007294-A1 | PSEUDO- AND NON-PEPTIDE BRADYKININ RECEPTOR ANTAGONISTS | SCIOS NOVA INC. (US) | 1995-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204485-A1 | STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | TTR, MAP1LC3B, SAAL1 | KEAP1 1409/4885PTPRB 2321/4885CDC25A 2324/4885 |
| US-11945806-B2 | Stabilization of amyloidogenic immunoglobulin light chains | TTR, MAP1LC3B, SAAL1 | KEAP1 1409/4885PTPRB 2321/4885CDC25A 2324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.