Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30476014 | 0.86 | SLC7A5 (0.46) | LTA4HCYP3A4CYP1A2CYP2C9LMNA | |
| SCHEMBL25318441 | 0.86 | SLC7A5 (0.46) | LTA4HCYP3A4CYP1A2CYP2C9LMNA | |
| SCHEMBL22445205 | 0.85 | ALDH1A1 (0.47) | ANPEPERAP2ERAP1CYP3A4CYP1A2 | |
| SCHEMBL2307682 | 0.83 | LTA4H (0.55) | LTA4HANPEPERAP2ERAP1 | |
| SCHEMBL27878054 | 0.83 | LTA4H (0.55) | LTA4HANPEPERAP2ERAP1 | |
| SCHEMBL2307679 | 0.83 | LTA4H (0.55) | LTA4HANPEPERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL29264506 | 0.82 | LTA4H (0.54) | LTA4HANPEPERAP2ERAP1 | |
| SCHEMBL8798260 | 0.82 | LTA4H (0.38) | LTA4HCYP3A4TBXAS1 | |
| SCHEMBL21591549 | 0.80 | LMNA (0.56) | CYP3A4LMNA | |
| SCHEMBL19068201 | 0.79 | ANPEP (0.56) | ANPEPERAP2ERAP1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091598-A2 | TREATMENT OF NEURODEGENERATIVE DISEASES | ICM (INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE) (FR) | 2018-05-24 | — | — | WO | disclosed |
| EP-3323415-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES | Institut du Cerveau et de la Moelle Epiniere-ICM (FR) | 2018-05-23 | — | — | EP | disclosed |