Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25318441 | 1.00 | SLC7A5 (0.46) | SLC7A5CYP3A4CYP1A2CYP2C9FDPS | |
| SCHEMBL1980092 | 0.90 | SLC7A5 (0.43) | SLC7A5CYP3A4CYP1A2CYP2C9FDPS | |
| SCHEMBL7337394 | 0.87 | ACACB (0.56) | KDM4EALDH1A1MAPTHTTLTA4H | |
| SCHEMBL7337381 | 0.87 | ACACB (0.56) | KDM4EALDH1A1MAPTHTTLTA4H | |
| SCHEMBL20162475 | 0.86 | LTA4H (0.44) | CYP3A4CYP1A2CYP2C9TBXAS1KDM4E | |
| SCHEMBL1676927 | 0.86 | MKNK1 (0.47) | — | |
| SCHEMBL1676925 | 0.86 | MKNK1 (0.47) | — | |
| SCHEMBL7378178 | 0.84 | CYP3A4 (0.48) | CYP3A4CYP1A2CYP2C9FDPSTBXAS1 | |
| SCHEMBL19699200 | 0.84 | ALDH1A1 (0.49) | CYP3A4CYP1A2CYP2C9FDPSTBXAS1 | |
| SCHEMBL29627252 | 0.84 | ALDH1A1 (0.49) | CYP3A4CYP1A2CYP2C9FDPSTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348109-B | Piperazine derivative, and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-116348109-A | Piperazine derivative, and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |