Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL781267 | 1.00 | KDM4E (0.38) | KDM4ETDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31343122 | 0.89 | KDM4E (0.40) | KDM4ETDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL382026 | 0.87 | KDM4E (0.36) | KDM4ETDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL22321965 | 0.87 | KDM4E (0.36) | KDM4ETDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7212934 | 0.86 | KDM4E (0.38) | KDM4ETDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL20162548 | 0.84 | KDM4E (0.34) | KDM4ETDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7795340 | 0.84 | SMN1; SMN2 (0.38) | KDM4ETDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL20856173 | 0.84 | SMN1; SMN2 (0.38) | KDM4ETDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7030455 | 0.84 | KDM4E (0.34) | KDM4ETDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL472178 | 0.82 | ALDH1A1 (0.38) | KDM4EALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118486-A1 | MONOSACCHARIDE PHOSPHORAMIDATE PRODRUGS | CERECOR INC. (US) | 2019-06-20 | — | — | WO | disclosed |
| EP-1928475-B1 | ANTIVIRAL PHOSPHORAMIDATES OF 4'-C-AZIDO-SUBSTITUTED PRONUCLEOTIDES | RIBOSCIENCE LLC (US) | 2018-05-23 | — | — | EP | disclosed |