Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030455 | 1.00 | KDM4E (0.34) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL382026 | 0.85 | KDM4E (0.36) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL22321965 | 0.85 | KDM4E (0.36) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL779563 | 0.85 | SMN1; SMN2 (0.37) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL20162518 | 0.84 | KDM4E (0.38) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL781267 | 0.84 | KDM4E (0.38) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL20856173 | 0.82 | SMN1; SMN2 (0.38) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7795340 | 0.82 | SMN1; SMN2 (0.38) | KDM4ETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL472185 | 0.81 | SIGMAR1 (0.33) | KDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL20162506 | 0.80 | ALDH1A1 (0.38) | KDM4EALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928475-B1 | ANTIVIRAL PHOSPHORAMIDATES OF 4'-C-AZIDO-SUBSTITUTED PRONUCLEOTIDES | RIBOSCIENCE LLC (US) | 2018-05-23 | — | — | EP | disclosed |