Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20856173 | 0.85 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2LMNATP53KDM4E | |
| SCHEMBL7795340 | 0.85 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2LMNATP53KDM4E | |
| SCHEMBL20856249 | 0.76 | POLB (0.33) | ALDH1A1SMN1; SMN2LMNATP53TSHR | |
| SCHEMBL472178 | 0.73 | ALDH1A1 (0.38) | ALDH1A1LMNAKDM4ETSHRMAPT | |
| SCHEMBL20162506 | 0.73 | ALDH1A1 (0.38) | ALDH1A1LMNAKDM4ETSHRMAPT | |
| SCHEMBL779563 | 0.73 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2LMNATP53KDM4E | |
| SCHEMBL22321965 | 0.73 | KDM4E (0.36) | ALDH1A1SMN1; SMN2LMNATP53KDM4E | |
| SCHEMBL382026 | 0.73 | KDM4E (0.36) | ALDH1A1SMN1; SMN2LMNATP53KDM4E | |
| SCHEMBL10004648 | 0.72 | ALOX15 (0.39) | ALDH1A1SMN1; SMN2LMNATP53KDM4E | |
| SCHEMBL17786771 | 0.72 | TSHR (0.39) | ALDH1A1SMN1; SMN2LMNATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928475-B1 | ANTIVIRAL PHOSPHORAMIDATES OF 4'-C-AZIDO-SUBSTITUTED PRONUCLEOTIDES | RIBOSCIENCE LLC (US) | 2018-05-23 | — | — | EP | disclosed |