Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | FNTA | P49354 | 4/20 | 0.31 |
| ▸ | FNTB | P49356 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22321970 | 0.89 | KMT2A (0.34) | POLBKMT2AL3MBTL1MMP1MMP2 | |
| SCHEMBL10004534 | 0.82 | NPC1 (0.36) | POLBALDH1A1MMP2MMP3MMP9 | |
| SCHEMBL20856173 | 0.80 | SMN1; SMN2 (0.38) | POLBKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL7795340 | 0.80 | SMN1; SMN2 (0.38) | POLBKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL7213785 | 0.77 | FNTA (0.35) | POLBKMT2AL3MBTL1MMP1MMP2 | |
| SCHEMBL20162538 | 0.76 | ALDH1A1 (0.35) | POLBKMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL4268833 | 0.73 | POLB (0.33) | POLBKMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL12501798 | 0.72 | TAS1R3 (0.35) | POLBKMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL20856237 | 0.72 | HSD17B10 (0.40) | MMP1MMP2MMP3MMP9 | |
| SCHEMBL7114956 | 0.71 | LAP3 (0.44) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078221-B2 | Phosphorodiamidates and other phosphorus derivatives of fingolimod and related S1P receptor modulators | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2021-08-03 | — | — | US | disclosed |
| US-20200255460-A1 | PHOSPHORODIAMIDATES AND OTHER PHOSPHORUS DERIVATIVES OF FINGOLIMOD AND RELATED S1 P RECEPTOR MODULATORS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2020-08-13 | — | — | US | disclosed |
| EP-3675869-A1 | PHOSPHORODIAMIDATES AND OTHER PHOSPHORUS DERIVATIVES OF FINGOLIMOD AND RELATED S1 P RECEPTOR MODULATORS | University College Cardiff Consultants Ltd (GB) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019064012-A1 | PHOSPHORODIAMIDATES AND OTHER PHOSPHORUS DERIVATIVES OF FINGOLIMOD AND RELATED S1 P RECEPTOR MODULATORS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078221-B2 | Phosphorodiamidates and other phosphorus derivatives of fingolimod and related S1P receptor modulators | S1PR1, S1PR3, S1PR4 | POLB 1523/4885KMT2A 912/4885ALDH1A1 3955/4885 |
| US-20200255460-A1 | PHOSPHORODIAMIDATES AND OTHER PHOSPHORUS DERIVATIVES OF FINGOLIMOD AND RELATED S1 P RECEPTOR MODULATORS | S1PR1, S1PR3, FFAR1 | POLB 1818/4885KMT2A 1306/4885ALDH1A1 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.