SCHEMBL2016269

SCHEMBL2016269

c1cncc(-c2cccc(-c3c4ccccc4c(-c4cccc(-c5cccnc5)n4)c4ccccc34)n2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.59
CYP19A1 P11511 3/20 0.56
CYP11B1 P15538 1/20 0.49
HSP90AA1 P07900 1/20 0.49
HSP90AB1 P08238 1/20 0.49
PTK2 Q05397 1/20 0.49
ALDH1A1 P00352 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
RAB9A P51151 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ABL1 P00519 1/20 0.46
EGFR P00533 1/20 0.46
PRKCA P17252 1/20 0.46
PRKCD Q05655 1/20 0.46
NPC1 O15118 2/20 0.46
IRAK4 Q9NWZ3 1/20 0.46
F2 P00734 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9973707 0.98 CYP2A6 (0.57) CYP2A6CYP19A1CYP11B1HSP90AA1HSP90AB1
SCHEMBL12259731 0.97 CYP19A1 (0.57) CYP2A6CYP19A1CYP11B1HSP90AA1HSP90AB1
SCHEMBL18101988 0.92 CYP19A1 (0.56) CYP2A6CYP19A1CYP11B1HSP90AA1HSP90AB1
SCHEMBL9973704 0.90 CYP2A6 (0.56) CYP2A6CYP19A1CYP11B1HSP90AA1HSP90AB1
SCHEMBL9973755 0.88 CYP2A6 (0.51) CYP2A6CYP19A1CYP11B1HSP90AA1HSP90AB1
SCHEMBL2020105 0.88 CYP19A1 (0.56) CYP2A6CYP19A1CYP11B1ALDH1A1CYP1A2
SCHEMBL9973772 0.88 CYP2A6 (0.50) CYP2A6CYP19A1CYP11B1HSP90AA1HSP90AB1
SCHEMBL9973760 0.87 CYP19A1 (0.51) CYP2A6CYP19A1CYP11B1HSP90AA1HSP90AB1
SCHEMBL9973777 0.87 CYP2A6 (0.53) CYP2A6CYP19A1CYP11B1HSP90AA1HSP90AB1
SCHEMBL3194702 0.87 CYP2A6 (0.74) CYP2A6CYP19A1HSP90AA1HSP90AB1PTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190214575-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC CORPORATION (JP) 2019-07-11 US disclosed
US-9954169-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2018-04-24 US disclosed
US-9954169-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2018-04-24 US disclosed
EP-2669262-B1 NOVEL ANTHRACENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC CORP (JP) 2018-03-07 EP disclosed
US-20180047913-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC CORPORATION (JP) 2018-02-15 US disclosed
US-9860960-B2 Organic EL display device and method for production of the same JOLED INC. (JP) 2018-01-02 US disclosed
US-9590182-B2 Benzofluorene compound, material for luminescent layer using said compound and organic electroluminescent device JNC CORPORATION (JP) 2017-03-07 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9105847-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2015-08-11 US disclosed
US-9105847-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2015-08-11 US disclosed
US-20110315963-A1 ORGANIC EL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-12-29 US disclosed
US-20110315963-A1 ORGANIC EL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-12-29 US disclosed
US-20110215310-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SK MATERIALS JNC CO., LTD. (KR) 2011-09-08 US disclosed
US-7964293-B2 Electron transport material and organic electroluminescent device using the same JNC CORPORATION (JP) 2011-06-21 US disclosed
US-7964293-B2 Electron transport material and organic electroluminescent device using the same JNC CORPORATION (JP) 2011-06-21 US disclosed
US-7964293-B2 Electron transport material and organic electroluminescent device using the same JNC CORPORATION (JP) 2011-06-21 US disclosed
US-20090134780-A1 Electron transport material and organic electroluminescent device using the same SK MATERIALS JNC CO., LTD. (KR) 2009-05-28 US disclosed
US-20090134780-A1 Electron transport material and organic electroluminescent device using the same SK MATERIALS JNC CO., LTD. (KR) 2009-05-28 US disclosed
US-20090134780-A1 Electron transport material and organic electroluminescent device using the same SK MATERIALS JNC CO., LTD. (KR) 2009-05-28 US disclosed
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device JNC CORPORATION (JP) 2008-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110215310-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SLC25A11, ELAVL1, SLC26A3 CYP2A6 4405/4885CYP19A1 3499/4885CYP11B1 1482/4885
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device LEF1, TRPA1, BRD8 CYP2A6 2384/4885CYP19A1 592/4885CYP11B1 2685/4885
US-20180047913-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE L1CAM, VDAC1, VDAC2 CYP2A6 3878/4885CYP19A1 2633/4885CYP11B1 4281/4885
US-20190214575-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE L1CAM, VDAC1, VDAC2 CYP2A6 3878/4885CYP19A1 2633/4885CYP11B1 4281/4885
US-20090134780-A1 Electron transport material and organic electroluminescent device using the same SLC25A11, ELAVL1, SLC26A3 CYP2A6 4405/4885CYP19A1 3499/4885CYP11B1 1482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.