Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20163296 | 0.95 | HDAC8 (0.56) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL20163304 | 0.86 | HDAC1 (0.60) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL18256331 | 0.81 | HDAC8 (0.73) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL1058606 | 0.81 | HDAC8 (0.54) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL18256339 | 0.80 | HDAC1 (0.77) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL1064490 | 0.80 | HDAC8 (0.56) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL15441220 | 0.78 | HDAC2 (0.61) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL1064045 | 0.77 | L3MBTL1 (0.59) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL31390534 | 0.76 | HDAC1 (0.54) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL1064950 | 0.73 | HDAC4 (0.64) | HDAC1HDAC8HDAC6HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141965-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141965-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | ENPP2, SPINT2, SERPINB1 | HDAC1 643/4885HDAC8 470/4885HDAC6 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.