Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6915427 | 0.82 | FEN1 (0.47) | CYP19A1SLC22A6NR3C1ALDH1A1GAA | |
| SCHEMBL517162 | 0.79 | SLC22A6 (0.47) | SLC22A6ALDH1A1GAAGPR84CYP2A6 | |
| SCHEMBL5141895 | 0.79 | IL1RN (0.47) | CYP19A1SLC22A6ALDH1A1 | |
| SCHEMBL9426286 | 0.79 | NSD2 (0.47) | CYP19A1SLC22A6NR3C1ALDH1A1GAA | |
| SCHEMBL29365920 | 0.79 | IL1RN (0.47) | CYP19A1SLC22A6ALDH1A1 | |
| SCHEMBL9442796 | 0.79 | PKM (0.48) | CYP19A1SLC22A6ALDH1A1GAAGPR84 | |
| SCHEMBL27148809 | 0.79 | SLC22A6 (0.50) | SLC22A6ALDH1A1GAAGPR84CYP2A6 | |
| SCHEMBL6918550 | 0.78 | CYP19A1 (0.47) | CYP19A1MGAMNR3C1ALDH1A1 | |
| SCHEMBL28939777 | 0.77 | SLC22A6 (0.49) | SLC22A6ALDH1A1GAAGPR84CYP2A6 | |
| SCHEMBL6923053 | 0.77 | PBRM1 (0.50) | SLC22A6ALDH1A1GAAGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180140578-A1 | METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND SELECTIVE TREATMENT OF CANCER | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-05-24 | — | — | US | disclosed |