SCHEMBL9426286

SCHEMBL9426286

CC(C)(C)NS(=O)(=O)c1c[nH]c2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 2/20 0.47
ATM Q13315 1/20 0.43
NR3C1 P04150 3/20 0.42
NR3C2 P08235 2/20 0.42
PKM P14618 1/20 0.42
TSHR P16473 1/20 0.41
LMNA P02545 1/20 0.41
NR4A2 P43354 1/20 0.41
CREBBP Q92793 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
CYP19A1 P11511 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
PGR P06401 1/20 0.41
PBRM1 Q86U86 1/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6915427 0.83 FEN1 (0.47) ATMNR3C1PKMTSHRLMNA
SCHEMBL20163593 0.79 CYP19A1 (0.50) NR3C1SLC22A6CYP19A1ALDH1A1GAA
SCHEMBL6918550 0.79 CYP19A1 (0.47) NR3C1PKMTSHRLMNACYP19A1
SCHEMBL6923053 0.78 PBRM1 (0.50) PKMTSHRLMNANR4A2CREBBP
SCHEMBL29557960 0.77 PBRM1 (0.52) ATMPKMTSHRNR4A2CREBBP
SCHEMBL15415994 0.77 PBRM1 (0.52) ATMPKMTSHRNR4A2CREBBP
SCHEMBL9442796 0.77 PKM (0.48) ATMPKMTSHRLMNANR4A2
SCHEMBL5141895 0.77 IL1RN (0.47) PKMTSHRSLC22A6CYP19A1ALDH1A1
SCHEMBL29365920 0.77 IL1RN (0.47) PKMTSHRSLC22A6CYP19A1ALDH1A1
SCHEMBL27148809 0.76 SLC22A6 (0.50) ATMSLC22A6ALDH1A1PBRM1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5356862-A Herbicidal sulfonylureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-18 US disclosed
EP-0511993-A1 HERBICIDAL SULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-11 EP disclosed
WO-1991010668-A1 HERBICIDAL SULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-25 WO disclosed