Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | KDM5A | P29375 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | NAAA | Q02083 | 2/20 | 0.59 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.57 |
| ▸ | KDM5C | P41229 | 1/20 | 0.57 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956332 | 0.94 | NAAA (0.68) | SMN1; SMN2KDM5AKDM4ENAAAKDM5B | |
| SCHEMBL7966788 | 0.94 | NAAA (0.68) | SMN1; SMN2KDM5AKDM4ENAAAKDM5B | |
| SCHEMBL9792819 | 0.90 | KDM4E (0.64) | SMN1; SMN2KDM5AKDM4ENAAAKDM5B | |
| SCHEMBL11627803 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM5AKDM4ENAAARXFP1 | |
| SCHEMBL7963734 | 0.83 | KDM4E (0.59) | SMN1; SMN2KDM5AKDM4EKDM5BKDM5C | |
| SCHEMBL16117373 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2NAAATSHRHTTL3MBTL1 | |
| SCHEMBL12308117 | 0.81 | KDM4E (0.64) | SMN1; SMN2KDM5AKDM4EKDM5BKDM5C | |
| SCHEMBL10242958 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2NAAARXFP1TSHRHTT | |
| SCHEMBL3634350 | 0.80 | NAAA (0.87) | SMN1; SMN2KDM4ENAAATSHRHTT | |
| SCHEMBL13383595 | 0.80 | KDM4E (0.84) | KDM5AKDM4EKDM5BKDM5CSMYD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759994-B2 | Luminogenic transition metal-based pyridyl complex and its use | CITY UNIVERSITY OF HONG KONG (HK) | 2020-09-01 | — | — | US | disclosed |
| US-10759994-B2 | Luminogenic transition metal-based pyridyl complex and its use | CITY UNIVERSITY OF HONG KONG (HK) | 2020-09-01 | — | — | US | disclosed |
| US-20180142144-A1 | LUMINOGENIC TRANSITION METAL-BASED PYRIDYL COMPLEX AND ITS USE | CITY UNIVERSITY OF HONG KONG (HK) | 2018-05-24 | — | — | US | disclosed |
| US-20180142144-A1 | LUMINOGENIC TRANSITION METAL-BASED PYRIDYL COMPLEX AND ITS USE | CITY UNIVERSITY OF HONG KONG (HK) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759994-B2 | Luminogenic transition metal-based pyridyl complex and its use | TK1, NOX5, PDXK | SMN1; SMN2 3154/4885KDM5A 2086/4885KDM4E 3901/4885 |
| US-20180142144-A1 | LUMINOGENIC TRANSITION METAL-BASED PYRIDYL COMPLEX AND ITS USE | TK1, NOX5, PDXK | SMN1; SMN2 3154/4885KDM5A 2086/4885KDM4E 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.