SCHEMBL20164222

SCHEMBL20164222

CCOC(=O)Nc1ccccc1OC(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.54
ALDH1A1 P00352 4/20 0.54
HPGD P15428 2/20 0.54
NPC1 O15118 4/20 0.51
RAB9A P51151 4/20 0.51
NR1I2 O75469 1/20 0.51
LMNA P02545 1/20 0.51
TP53 P04637 1/20 0.51
AHR P35869 1/20 0.51
TAAR1 Q96RJ0 1/20 0.51
SLC6A3 Q01959 1/20 0.50
SMN1; SMN2 Q16637 5/20 0.49
GAA P10253 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
MAPT P10636 1/20 0.47
MEN1 O00255 1/20 0.47
CRHBP P24387 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18249405 0.89 KMT2A (0.67) KMT2AALDH1A1HPGDNPC1RAB9A
SCHEMBL20164263 0.88 KMT2A (0.49) KMT2AALDH1A1HPGDNPC1RAB9A
SCHEMBL20164238 0.87 ALDH1A1 (0.56) KMT2AALDH1A1HPGDNPC1RAB9A
SCHEMBL18249387 0.86 ALDH1A1 (0.52) KMT2AALDH1A1HPGDNPC1RAB9A
SCHEMBL20164221 0.84 HPGD (0.52) KMT2AALDH1A1HPGDNPC1RAB9A
SCHEMBL18249435 0.84 ALDH1A1 (0.57) KMT2AALDH1A1HPGDSMN1; SMN2GAA
SCHEMBL27464722 0.83 KMT2A (0.60) KMT2AALDH1A1NPC1RAB9ANR1I2
SCHEMBL20164276 0.82 MAPT (0.48) KMT2AALDH1A1HPGDNPC1RAB9A
SCHEMBL18249430 0.82 KMT2A (0.56) KMT2AALDH1A1HPGDNPC1RAB9A
SCHEMBL10930815 0.80 HSD17B10 (0.59) KMT2AALDH1A1HPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107580607-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2019-09-27 CN disclosed
EP-3298048-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2019-07-03 EP disclosed
US-10221256-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2019-03-05 US disclosed
US-20180142044-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-05-24 US disclosed
CN-107580607-A CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS 巴塞尔聚烯烃意大利有限公司 2018-01-12 CN disclosed