Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164233 | 0.90 | KMT2A (0.49) | HPGDALDH1A1MAOBKMT2ACYP1A2 | |
| SCHEMBL20164222 | 0.84 | KMT2A (0.54) | HPGDALDH1A1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL20164238 | 0.82 | ALDH1A1 (0.56) | HPGDALDH1A1MAOBKMT2ACYP1A2 | |
| SCHEMBL20164276 | 0.81 | MAPT (0.48) | HPGDALDH1A1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL20164217 | 0.78 | KDM4E (0.55) | HPGDALDH1A1KMT2ARAB9AMAPK1 | |
| SCHEMBL20164271 | 0.78 | ALDH1A1 (0.60) | HPGDALDH1A1MAOBKMT2ACYP1A2 | |
| SCHEMBL18249480 | 0.76 | SMN1; SMN2 (0.55) | HPGDALDH1A1MAOBKMT2ACYP1A2 | |
| SCHEMBL18249430 | 0.75 | KMT2A (0.56) | HPGDALDH1A1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL3829756 | 0.75 | ALDH1A1 (0.60) | HPGDALDH1A1MAOBKMT2ACYP1A2 | |
| SCHEMBL8304601 | 0.75 | ALDH1A1 (0.60) | HPGDALDH1A1MAOBKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |