Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164252 | 0.90 | KMT2A (0.51) | ALDH1A1HPGDKMT2ACYP1A2CYP2C9 | |
| SCHEMBL20164222 | 0.87 | KMT2A (0.54) | ALDH1A1HPGDKMT2ACYP1A2CYP2C9 | |
| SCHEMBL20164221 | 0.82 | HPGD (0.52) | ALDH1A1HPGDKMT2ACYP1A2CYP2C9 | |
| SCHEMBL19656079 | 0.82 | KMT2A (0.58) | HPGDKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15233903 | 0.81 | LMNA (0.48) | ALDH1A1KMT2ASLC6A3SMN1; SMN2LMNA | |
| SCHEMBL15535035 | 0.80 | TSHR (0.53) | ALDH1A1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18249430 | 0.79 | KMT2A (0.56) | ALDH1A1HPGDKMT2ACYP1A2CYP2C9 | |
| SCHEMBL18249405 | 0.78 | KMT2A (0.67) | ALDH1A1HPGDKMT2ACYP1A2CYP2C9 | |
| SCHEMBL18249387 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HPGDKMT2ASMN1; SMN2LMNA | |
| SCHEMBL12355077 | 0.77 | KMT2A (0.61) | KMT2ASLC6A3SMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |