SCHEMBL20164263

SCHEMBL20164263

CCCc1ccc(C(=O)Oc2ccccc2NC(=O)OCC)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
LMNA P02545 2/20 0.49
NR1I2 O75469 1/20 0.49
TP53 P04637 1/20 0.49
AHR P35869 1/20 0.49
TAAR1 Q96RJ0 1/20 0.49
ALDH1A1 P00352 4/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.45
POLB P06746 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
GAA P10253 2/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
MEN1 O00255 2/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20164222 0.88 KMT2A (0.54) KMT2ANPC1RAB9ALMNANR1I2
SCHEMBL18249405 0.86 KMT2A (0.67) KMT2ANPC1RAB9ALMNANR1I2
SCHEMBL18249407 0.84 NLRP3 (0.48) KMT2ANPC1RAB9ALMNATP53
SCHEMBL20164229 0.82 SMN1; SMN2 (0.43) KMT2ANPC1RAB9ALMNAALDH1A1
SCHEMBL20164212 0.81 ALDH1A1 (0.53) KMT2ALMNAALDH1A1HPGDSMN1; SMN2
SCHEMBL28190980 0.81 ALDH1A1 (0.42) KMT2ANPC1RAB9AALDH1A1HPGD
SCHEMBL18249473 0.79 SMN1; SMN2 (0.50) KMT2AALDH1A1SMN1; SMN2GAAMEN1
SCHEMBL18249435 0.78 ALDH1A1 (0.57) KMT2AALDH1A1HPGDSMN1; SMN2L3MBTL1
SCHEMBL16765599 0.78 RXRA (0.50) KMT2ANPC1RAB9ALMNASMN1; SMN2
SCHEMBL18249387 0.78 ALDH1A1 (0.52) KMT2ANPC1RAB9ALMNANR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107580607-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2019-09-27 CN disclosed
EP-3298048-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2019-07-03 EP disclosed
US-10221256-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2019-03-05 US disclosed
US-20180142044-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-05-24 US disclosed
CN-107580607-A CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS 巴塞尔聚烯烃意大利有限公司 2018-01-12 CN disclosed