Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164295 | 0.93 | L3MBTL1 (0.41) | TP53ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL20164270 | 0.91 | LMNA (0.42) | TP53ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL20164240 | 0.91 | NR1H4 (0.39) | TP53ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL18249379 | 0.88 | KMT2A (0.39) | TP53ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL20164290 | 0.85 | RAB9A (0.35) | TP53ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL20164267 | 0.85 | TP53 (0.38) | TP53ALDH1A1LMNAHSD17B10L3MBTL1 | |
| SCHEMBL20164273 | 0.84 | MAPT (0.43) | ALDH1A1LMNAPOLBL3MBTL1MAPT | |
| SCHEMBL20164286 | 0.83 | GAA (0.38) | TP53ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL28320818 | 0.81 | NPSR1 (0.37) | TP53ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL20164243 | 0.81 | MAPT (0.40) | ALDH1A1LMNAPOLBL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |