Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 8/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20164671 | 0.99 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2SLC29A1SYKAURKB | |
| SCHEMBL20164445 | 0.85 | SLC29A1 (0.55) | ALDH1A1SMN1; SMN2SLC29A1CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL20164699 | 0.84 | SLC29A1 (0.53) | ALDH1A1SMN1; SMN2SLC29A1CYP3A4KDM4E | |
| SCHEMBL20164368 | 0.83 | SLC29A1 (0.40) | ALDH1A1SMN1; SMN2SLC29A1CYP3A4KDM4E | |
| SCHEMBL20164750 | 0.82 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2SLC29A1SYKCYP3A4 | |
| Hydrochloric Acid SCHEMBL20164524 | 0.81 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2SLC29A1SYKCYP3A4 | |
| Hydrochloric Acid SCHEMBL20164751 | 0.81 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2SLC29A1CYP3A4KDM4E | |
| SCHEMBL20164356 | 0.80 | KHK (0.49) | ALDH1A1SMN1; SMN2SLC29A1KHK | |
| Hydrochloric Acid SCHEMBL20164580 | 0.79 | KHK (0.48) | ALDH1A1SMN1; SMN2SLC29A1KHK | |
| SCHEMBL20164646 | 0.79 | SLC29A1 (0.44) | ALDH1A1SMN1; SMN2SLC29A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3316890-B1 | NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME | NEURAD LTD (IL) | 2023-09-06 | — | — | EP | disclosed |
| US-10294228-B2 | Breathing control modulating compounds, and methods of making and using same | NEURAD LTD. (IL) | 2019-05-21 | — | — | US | disclosed |
| US-20180141953-A1 | Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same | NEURAD LTD. (IL) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141953-A1 | Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same | MTNR1B, CHRM3, PER2 | ALDH1A1 2164/4885SMN1; SMN2 463/4885SLC29A1 4472/4885 |
| US-10294228-B2 | Breathing control modulating compounds, and methods of making and using same | MTNR1B, PDE3A, CHRM3 | ALDH1A1 2004/4885SMN1; SMN2 454/4885SLC29A1 4518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.