SCHEMBL20164646

SCHEMBL20164646

CCCNc1nc(N(C)C)nc2c(NCC(C)(C)O)ncnc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 5/20 0.44
KHK P50053 2/20 0.34
ALDH1A1 P00352 2/20 0.33
HTT P42858 2/20 0.33
KDM4E B2RXH2 2/20 0.33
USP2 O75604 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CHRM4 P08173 1/20 0.33
POLB P06746 1/20 0.33
CCNC P24863 1/20 0.32
CDK8 P49336 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
RAF1 P04049 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ABL1 P00519 1/20 0.32
SRC P12931 1/20 0.32
CCNB2 O95067 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20164760 0.99 SLC29A1 (0.43) SLC29A1KHKALDH1A1HTTKDM4E
SCHEMBL25378008 0.89 SLC29A1 (0.43) SLC29A1KHKALDH1A1HTTKDM4E
Hydrochloric Acid SCHEMBL20164715 0.88 SLC29A1 (0.42) SLC29A1KHKALDH1A1HTTKDM4E
SCHEMBL20164445 0.85 SLC29A1 (0.55) SLC29A1KHKALDH1A1HTTKDM4E
Hydrochloric Acid SCHEMBL20164699 0.84 SLC29A1 (0.53) SLC29A1KHKALDH1A1HTTKDM4E
SCHEMBL20164612 0.84 SLC29A1 (0.34) SLC29A1ALDH1A1KDM4E
SCHEMBL20164527 0.83 SLC29A1 (0.52) SLC29A1KHKALDH1A1HTTKDM4E
SCHEMBL20164418 0.83 KCNH2 (0.34) KHKCHRM4
SCHEMBL20164337 0.83 KHK (0.46) KHK
Hydrochloric Acid SCHEMBL20164691 0.83 SLC29A1 (0.33) SLC29A1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US claimed
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF NEURIM PHARMACEUTICALS (1991) LTD. (IL) 2025-02-20 US disclosed
EP-3316890-B1 NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME NEURAD LTD (IL) 2023-09-06 EP disclosed
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same NEURAD LTD. (IL) 2019-05-21 US disclosed
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same MTNR1B, CHRM3, PER2 SLC29A1 4472/4885KHK 3022/4885ALDH1A1 2164/4885
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF GPR119, GPR35, GPR55 SLC29A1 2077/4885KHK 578/4885ALDH1A1 4280/4885
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same MTNR1B, PDE3A, CHRM3 SLC29A1 4518/4885KHK 2826/4885ALDH1A1 2004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.