Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012015 | 0.86 | HCAR2 (0.44) | — | |
| SCHEMBL2015417 | 0.78 | HIF1A (0.43) | MAPK1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL28117989 | 0.72 | PARP1 (0.47) | MAPK1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL9938469 | 0.71 | MAPK1 (0.50) | MAPK1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL28007224 | 0.70 | MAOA (0.52) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL902640 | 0.70 | ALDH1A1 (0.52) | MAPK1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL9938264 | 0.69 | BRD4 (0.51) | MAPK1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL9938380 | 0.69 | MRGPRX4 (0.68) | MAPK1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL8883145 | 0.69 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL1656083 | 0.68 | EGLN2 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |